An odd fault has suddenly developed in my data base. Now and again a pofile will appear in the drop-down list on the left that when I click to edit or remove it opens up or removes the disc immediately above or below. If I remove the discs above and below the fault carries on to the next one. I have tried a complete restore but was told it had aborted and could not be carried out. Any ideas?

Yes tried repair but it seemed not to work as did a partial restore of the affected profiles. I had backed up only a few days ago, but then tried it again with a full restore and suddenly restore worked and with only the need to re-make a few corrections post the previous restore it is now OK. Odd as I have never had such a problem before, suggest all users do regular full restores. Thanks to Blair for comment

This has happened to me as well.  Generally after I have added manual profiles and reset collection numbers.  I have found that if I run Database Repair twice it clears up.