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What kind of error is reported by Windows? Access-violation or something different?
If it is an access violation what CPU do you use?
In any case try to post a screenshot of the errormessage (with details).

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What security software is running (virus / firewall / anti-spyware / etc)?
Does the error occur with all of these disabled?

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When you rebuilt your system did you use "tuning software" to improve the performance of your PC?
If yes, which program did you use and which settings were made?

Is the latest version of the NetFramework running on your Computer?

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EDIT: Is your computer supplied with the latest updates? Try running "Windows Update" and install all applicable updates (except the additional programs which are not needed, like Messenger, Silverlight, etc)

Sorry if this seems a little like fishing in the dark, but you didn't give us too much to start with.

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That could be a difficult one?
what is your confiuration?
XP Pro and in what language is it running?
you could download these and run the programs:

SIW - System Information for Windows

there from download, download the installer, install the program and run it.
It will you give you a lot of information:
1) Operating system:

From this screen we need the
- name of your XP Pro
- Windows Update's version number
2) Hardware System Info:

From this screen we need the
- Manufacturer
- Product Name
3) CPU info

From this screen we need the
- Number of CPU(S)
- Vendor
- CPU Full Name

[li]process explorer
[/li]make a folder Process Explorer in your c:\Program Files\
unpack the zip file and copy those 3 files in there.
run the program
go to its menu: options
choose the second option: Replace Task Manager
go to its menu view: select bottom option: Select columns
[x] Description
[x] Company Name
[x] Version
click OK
Now you exit the program: File: Exit
next step press simultaneously these 3 keys: [Ctrl] [Alt] [Delete]
the program starts up and displays all running programs like this:
This an Dutch XP PRO 5.01.2600.2180 running very clean:

all we have to do now is find some one with an comparable XP Pro on simular hardware that has DVD Profiler running and compare the differences. The program allows also to shut down running Process Tree. You just right click on a process like iptray (temperature control program in this case) and select Kill Process Tree
- uninstall DVD Profiler
- Download DVD Profiler 3.1.1 (Build 1171) here
- close all not essential programs
- set your desktop to a standard resolution if not the case (1024 x 768 pixels)
- see if the program runs, if error, report the error here.

do you have an upload possibility for screendumps? If not take a free account at Photobucket. When uploading screendumps be carefull not to include your software serial numbers (XP Pro, ...)

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We all have paid for our software and DVD Profiler is running happy on a standard installed Windows XP Pro, as you can see by the  last screenshot. The last program in that screenshot is a running DVD Profiler. So we are trying to help you to figure out why yours is not running. To even try we need some basic information. How else can we locate the problem. There is a lot of folk arround willing to give you their time.

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My personal proposal:

If you have a recent backup file (ends with *.dpb) try this (if not, you have to start from scratch after this procedure...):

Uninstall current profiler and remove all existing profiler files including the profiler related files in the "my documets" folder (e.g. C:\documents and Settings\<user>\Application Data\DVD Profiler).

Install the latest profiler and start the programme with an empty database. Does the programme crash? No? If not restore now your backup file. If the programme crashes now after a restart, the problem could be your existing backup file (corrupt and/or incompatible to the current profiler version).

Disclaimer:
Please consider this just as a personal recommendation; I'm not tech support but I try to provide some ideas for your problem solution!